SCHEMBL25486204

SCHEMBL25486204

C=CC(=O)OCCCCCCCCCCCCOC1CCC(C(=O)Oc2ccc(OC(=O)C#Cc3ccc(OCCCCCCCCCCCOC(=O)C=C)cc3)cc2)CC1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
TSHR P16473 2/20 0.35
ALDH1A1 P00352 2/20 0.35
CYP3A4 P08684 1/20 0.35
HTT P42858 3/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ACACB O00763 6/20 0.32
ELANE P08246 1/20 0.32
KCNH2 Q12809 1/20 0.31
HPGD P15428 2/20 0.31
MEN1 O00255 1/20 0.31
HSP90AA1 P07900 1/20 0.30
PTPN2 P17706 1/20 0.30
PTPN1 P18031 1/20 0.30
PTPN6 P29350 1/20 0.30
PTPN11 Q06124 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25486199 1.00 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486198 1.00 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486278 1.00 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486389 1.00 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL21400658 0.93 THRB (0.33) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL21400381 0.91 TSHR (0.40) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486164 0.90 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486167 0.90 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486172 0.90 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT
SCHEMBL25486183 0.90 THRB (0.37) THRBTSHRALDH1A1CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151275-A1 COMPOUND, COMPOSITION FOR ANISOTROPIC DYE FILMS INCLUDING THE COMPOUND, ANISOTROPIC DYE FILM, AND OPTICAL ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2023-05-18 US disclosed