Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 3/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23126 | 0.82 | ALDH1A1 (0.53) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL11436629 | 0.79 | ALDH1A1 (0.50) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL17818674 | 0.79 | ALDH1A1 (0.50) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL27930574 | 0.75 | HMGCR (0.37) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL7684976 | 0.74 | ALDH1A1 (0.35) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL10345101 | 0.74 | ALDH1A1 (0.35) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL4759426 | 0.74 | ALDH1A1 (0.45) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL7770808 | 0.72 | CYP2C19 (0.48) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL27727275 | 0.72 | ALDH1A1 (0.33) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 | |
| SCHEMBL27589221 | 0.72 | ALDH1A1 (0.33) | CYP2C19HIF1ACYP2D6TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096261-A | A kind of preparation method of Fimasartan | 四川海思科制药有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-103119208-A | A biocidal polyolefin yarn with 3-12 filaments | VESTERGAARD FRANDSEN SA | 2013-05-22 | — | — | CN | claimed |
| WO-2011124228-A1 | A BIOCIDAL POLYOLEFIN YARN WITH 3-12 FILAMENTS | VESTERGAARD FRANDSEN SA (CH) | 2011-10-13 | — | — | WO | claimed |
| WO-2011124227-A1 | BIOCIDAL ACID-ADJUSTED POLYMER WITH POLYPROPYLENE | VESTERGAARD FRANDSEN SA (CH) | 2011-10-13 | — | — | WO | claimed |
| CN-106380729-B | Novel PVC heat stabilizer | 邵卫东 | 2019-01-29 | — | — | CN | disclosed |
| CN-109096261-A | A kind of preparation method of Fimasartan | 四川海思科制药有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-109096261-A | A kind of preparation method of Fimasartan | 四川海思科制药有限公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-107973784-A | Synthesis method of fimasartan | 珠海市海瑞德生物科技有限公司 | 2018-05-01 | — | — | CN | disclosed |
| CN-106380729-A | Novel PVC heat stablizer | 邵卫东 | 2017-02-08 | — | — | CN | disclosed |
| CN-103119208-A | A biocidal polyolefin yarn with 3-12 filaments | VESTERGAARD FRANDSEN SA | 2013-05-22 | — | — | CN | disclosed |
| WO-2011124227-A1 | BIOCIDAL ACID-ADJUSTED POLYMER WITH POLYPROPYLENE | VESTERGAARD FRANDSEN SA (CH) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011124228-A1 | A BIOCIDAL POLYOLEFIN YARN WITH 3-12 FILAMENTS | VESTERGAARD FRANDSEN SA (CH) | 2011-10-13 | — | — | WO | disclosed |
| CN-1290501-C | Pharmaceutically active isoindoline derivatives | CELGENE CORP (US) | 2006-12-20 | — | — | CN | disclosed |
| CN-1575174-A | Pharmaceutically active isoindoline derivatives | CELGENE CORP (US) | 2005-02-02 | — | — | CN | disclosed |
| CN-1295565-A | Barbituric acid derivative and preventive and therapeutic agent for bone and cartilage containing the same | HOECHST MARION ROUSSEL INC (FR) | 2001-05-16 | — | — | CN | disclosed |
| CN-1055617-C | Oral medicament form | MERCK PATENT GMBH (DE) | 2000-08-23 | — | — | CN | disclosed |
| CN-1090171-A | Oral Pharmaceutical dosage forms | MERCK PATENT GMBH (DE) | 1994-08-03 | — | — | CN | disclosed |
| US-4382972-A | Flavoring compositions and flavored comestibles containing alkyl 2,3-dihydro-3(1'-hydroxyalkylidene)-2-oxo-5-alkylfuran-4-carboxylates | FRITZSCHE DODGE & OLCOTT INC. (US) | 1983-05-10 | — | — | US | disclosed |