⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55096 | 0.85 | DAO (0.38) | — | |
| SCHEMBL16197726 | 0.83 | CHRM2 (0.52) | — | |
| SCHEMBL16467352 | 0.82 | CHRM2 (0.37) | — | |
| SCHEMBL18294965 | 0.79 | PDE5A (0.33) | — | |
| SCHEMBL18659945 | 0.79 | — | — | |
| SCHEMBL182997 | 0.79 | CHRM2 (0.44) | — | |
| SCHEMBL632041 | 0.77 | CHRM2 (0.47) | — | |
| SCHEMBL22192851 | 0.77 | CHRM2 (0.42) | — | |
| SCHEMBL19049630 | 0.76 | ALOX5 (0.40) | — | |
| Ether SCHEMBL17606594 | 0.76 | CHRM2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-11771738-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230286997-A1 | Compounds for the Treatment of Cancer and Inflammatory Disease | SHY Therapeutics LLC | 2023-09-14 | — | — | US | disclosed |
| US-10881666-B2 | Combination pharmaceutical agents as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| EP-3541792-B1 | TRIAZOLE FURAN COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| US-20190192535-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2019-06-27 | — | — | US | disclosed |
| WO-2019038250-A1 | BORONIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-02-28 | — | — | WO | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |
| WO-2017142852-A1 | COELENTERAZINE ANALOGUES | PROMEGA CORPORATION (US) | 2017-08-24 | — | — | WO | disclosed |
| US-7985765-B2 | Therapeutic substituted pyrroles | ALLERGAN, INC. (US) | 2011-07-26 | — | — | US | disclosed |
| WO-2010056717-A1 | SUBSTITUTED BICYCLIC AMINES FOR THE TREATMENT OF DIABETES | MERCK SHARP & DOHME CORP. (US) | 2010-05-20 | — | — | WO | disclosed |
| US-7692030-B2 | Conjugates of artemisinin-related endoperoxides and hydrazone derivatives for the treatment of cancer | UNIVERSITY OF WASHINGTON (US) | 2010-04-06 | — | — | US | disclosed |
| US-7692030-B2 | Conjugates of artemisinin-related endoperoxides and hydrazone derivatives for the treatment of cancer | UNIVERSITY OF WASHINGTON (US) | 2010-04-06 | — | — | US | disclosed |
| US-20100048664-A1 | THERAPEUTIC SUBSTITUTED PYRROLES | ALLERGAN, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-7642265-B2 | Benzimidazoles and analogs thereof as antivirals | ISIS PHARMACEUTICALS, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| WO-2008118724-A1 | INDOLE CARBOXAMIDES AS IKK2 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-02 | — | — | WO | disclosed |
| US-20080103192-A1 | CONJUGATES OF ARTEMISININ-RELATED ENDOPEROXIDES AND HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER | WASHINGTON, UNIVERSITY OF (US) | 2008-05-01 | — | — | US | disclosed |
| US-20080103192-A1 | CONJUGATES OF ARTEMISININ-RELATED ENDOPEROXIDES AND HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER | WASHINGTON, UNIVERSITY OF (US) | 2008-05-01 | — | — | US | disclosed |
| WO-2008046109-A2 | CONJUGATES OF ARTEMISININ-RELATED ENDOPEROXIDES AND HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER | UNIVERSITY OF WASHINGTON (US) | 2008-04-17 | — | — | WO | disclosed |