Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 5/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827158 | 0.84 | UCHL1 (0.38) | GSK3BGSK3AHTR2CHTR2AUCHL1 | |
| SCHEMBL25827157 | 0.83 | HTR2C (0.40) | HTR2CHTR2AUCHL1CYP11B1CYP11B2 | |
| SCHEMBL25820801 | 0.81 | UCHL1 (0.43) | GSK3BGSK3AHTR2CUCHL1HTR2B | |
| SCHEMBL25820804 | 0.80 | UCHL1 (0.45) | HTR2CHTR2AUCHL1CYP11B1CYP11B2 | |
| SCHEMBL24010363 | 0.80 | HTR2C (0.38) | GSK3BGSK3AMAPK8MAPK10HTR2C | |
| SCHEMBL24010364 | 0.79 | HTR2C (0.39) | HTR2CHTR2AUCHL1CYP11B1CYP11B2 | |
| SCHEMBL25488283 | 0.75 | GAK (0.40) | KDRMET | |
| SCHEMBL25488379 | 0.74 | GRM5 (0.49) | GSK3BMAPK8MAPK10MAPT | |
| SCHEMBL25820817 | 0.74 | UCHL1 (0.41) | GSK3BGSK3AMAPK8MAPK10HTR2C | |
| SCHEMBL25820818 | 0.74 | UCHL1 (0.42) | HTR2CUCHL1CYP11B1CYP11B2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |