⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793804 | 0.77 | — | — | |
| SCHEMBL30436044 | 0.77 | — | — | |
| SCHEMBL2844671 | 0.73 | — | — | |
| SCHEMBL13101476 | 0.72 | CHRM2 (0.40) | — | |
| SCHEMBL11378220 | 0.69 | — | — | |
| SCHEMBL2127534 | 0.69 | — | — | |
| SCHEMBL1186531 | 0.68 | CYP1A2 (0.37) | — | |
| SCHEMBL5728422 | 0.68 | — | — | |
| SCHEMBL4273120 | 0.67 | ALDH1A1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL6622694 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129044-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2025-04-24 | — | — | US | disclosed |
| US-11661410-B2 | Tricyclic compounds as histone methyltransferase inhibitors | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-20230150972-A1 | PYRIDINYL DERIVATIVES AS SODIUM CHANNEL ACTIVATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-05-18 | — | — | US | disclosed |