SCHEMBL2548993

SCHEMBL2548993

COc1ccccc1/C=N/c1cccc2c1ccc1ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.46
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
MAPT P10636 3/20 0.44
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.44
DHODH Q02127 1/20 0.44
HPGD P15428 4/20 0.43
KDM4E B2RXH2 3/20 0.43
ALDH1A1 P00352 4/20 0.43
PKM P14618 1/20 0.43
CHAT P28329 1/20 0.43
APAF1 O14727 1/20 0.42
ATM Q13315 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
CYP1A1 P04798 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2288123 0.91 POLB (0.57) POLBL3MBTL1SMN1; SMN2MEN1KMT2A
SCHEMBL1727879 0.91 POLB (0.57) POLBL3MBTL1SMN1; SMN2MEN1KMT2A
SCHEMBL1728372 0.77 GAA (0.49) POLBSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL1728371 0.77 GAA (0.49) POLBSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL22299609 0.77 IDO1 (0.51) L3MBTL1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL1005616 0.75 MAPT (0.59) L3MBTL1SMN1; SMN2MEN1KMT2AMAPT
SCHEMBL28320760 0.74 DHODH (0.59) POLBL3MBTL1MEN1KMT2AMAPT
SCHEMBL27865804 0.74 MAPT (0.48) SMN1; SMN2MEN1KMT2AMAPTNPC1
SCHEMBL19732203 0.71 L3MBTL1 (0.50) POLBL3MBTL1SMN1; SMN2MEN1KMT2A
SCHEMBL2547530 0.71 KDM4E (0.47) SMN1; SMN2MEN1KMT2AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553520-A1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE Ravenbrick, LLC (US) 2013-02-06 EP disclosed
WO-2011123457-A1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2011-10-06 WO disclosed