Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK6 | Q16659 | 5/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29312307 | 1.00 | MAPK6 (0.44) | MAPK6CYP11B1CYP11B2MAPTRAB9A | |
| SCHEMBL15204865 | 0.90 | CYP11B1 (0.49) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| SCHEMBL15204867 | 0.90 | CYP11B1 (0.49) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| SCHEMBL15221643 | 0.90 | CYP11B1 (0.49) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| Hydrochloric Acid SCHEMBL15204797 | 0.89 | CYP11B1 (0.48) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| SCHEMBL15221612 | 0.89 | RAB9A (0.47) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| Hydrochloric Acid SCHEMBL15204688 | 0.87 | RAB9A (0.46) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| Hydrochloric Acid SCHEMBL15204377 | 0.87 | RAB9A (0.46) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| Hydrochloric Acid SCHEMBL15204689 | 0.87 | RAB9A (0.46) | CYP11B1CYP11B2MAPTRAB9AHCAR3 | |
| Hydrochloric Acid SCHEMBL15204378 | 0.87 | RAB9A (0.46) | CYP11B1CYP11B2MAPTRAB9AHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023084449-A1 | DIAMINOCYCLOPENTYLPYRIDINE DERIVATIVES FOR THE TREATMENT OF A DISEASE OR DISORDER | NOVARTIS AG (CH) | 2023-05-19 | — | — | WO | disclosed |