Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.42 |
| ▸ | HPN | P05981 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384476 | 0.91 | USP2 (0.47) | HTTNPC1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL25561581 | 0.86 | USP2 (0.43) | HTTNPC1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL14870877 | 0.84 | SMN1; SMN2 (0.49) | HTTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27385413 | 0.84 | HTT (0.44) | HTTNPC1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL19633842 | 0.83 | SMN1; SMN2 (0.48) | HTTNPC1RAB9ASMN1; SMN2PLAU | |
| SCHEMBL12698542 | 0.82 | HTT (0.48) | HTTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL23071857 | 0.80 | KMT2A (0.42) | HTTNPC1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL24252193 | 0.79 | SMN1; SMN2 (0.51) | HTTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL23432921 | 0.78 | HTT (0.39) | HTTNPC1RAB9AUSP2SMN1; SMN2 | |
| SCHEMBL25489515 | 0.78 | HTT (0.46) | HTTUSP2PLAUHPNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158154-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A CAMPTOTHECIN MOIETY | TUBULIS GMBH (DE) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158154-A1 | CONJUGATES COMPRISING A PHOSPHORUS (V) AND A CAMPTOTHECIN MOIETY | CALCR, PTH1R, BCR | HTT 4221/4885NPC1 3030/4885RAB9A 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.