SCHEMBL25491483

SCHEMBL25491483

COCCNc1cc(NC(=O)c2cn(C(C)C)c3cc(C=O)c(C4OCCO4)nc23)ncc1C#N

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FGFR4 P22455 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30385913 0.86 FGFR4 (0.78) FGFR4
SCHEMBL25190398 0.86 FGFR4 (0.78) FGFR4
SCHEMBL30386350 0.83 FGFR4 (0.79) FGFR4
SCHEMBL25189828 0.83 FGFR4 (0.79) FGFR4
SCHEMBL25193340 0.83 FGFR4 (1.00) FGFR4
SCHEMBL30386158 0.82 FGFR4 (0.81) FGFR4
SCHEMBL25187980 0.82 FGFR4 (0.81) FGFR4
SCHEMBL30437750 0.81 FGFR4 (0.73) FGFR4
SCHEMBL25491205 0.81 FGFR4 (0.73) FGFR4
SCHEMBL25201462 0.81 FGFR4 (1.00) FGFR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023082044-A1 5-FORMYL HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF 暨南大学 2023-05-19 — — WO disclosed
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