Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 17/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23999830 | 0.80 | KDR (0.44) | KDRMAPKAPK2MET | |
| SCHEMBL23999898 | 0.80 | KDR (0.56) | KDRMAPKAPK2MET | |
| SCHEMBL30180457 | 0.80 | KDR (0.56) | KDRMAPKAPK2MET | |
| SCHEMBL30180450 | 0.78 | KDR (0.53) | KDRMAPKAPK2PARP1MET | |
| SCHEMBL23999675 | 0.78 | KDR (0.53) | KDRMAPKAPK2PARP1MET | |
| SCHEMBL18617616 | 0.74 | KDR (0.75) | KDRMET | |
| SCHEMBL26325453 | 0.74 | KDR (0.62) | KDRMAPKAPK2MET | |
| SCHEMBL23999699 | 0.74 | KDR (0.63) | KDRMAPKAPK2MET | |
| SCHEMBL30180360 | 0.74 | KDR (0.63) | KDRMAPKAPK2MET | |
| SCHEMBL23999511 | 0.74 | KDR (0.63) | KDRMAPKAPK2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |