SCHEMBL2549570

SCHEMBL2549570

C=C(C)C(=O)OCCC[Si](C)(OC)OCC

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
THRB P10828 1/20 0.47
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28863333 0.95 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL218857 0.93 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL63717 0.92 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL5191072 0.91 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL220912 0.91 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28347564 0.91 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL35128 0.91 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT
SCHEMBL8188277 0.90 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1098411 0.90 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
Alcohol SCHEMBL28778173 0.89 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
CN-111793345-B Plastic spring and preparation method and application thereof 宁波金雨科技实业有限公司 2022-06-28 CN disclosed
CN-111793345-A Plastic spring and preparation method and application thereof 宁波金雨科技实业有限公司 2020-10-20 CN disclosed
US-20170200615-A1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND (ZHEJIANG) NEW MATERIALS CO., LTD (CN) 2017-07-13 US disclosed
US-9564339-B2 Etch resistant alumina based coatings PIBOND OY (FI) 2017-02-07 US disclosed
US-20130143408-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2013-06-06 US disclosed
EP-2553145-A1 ETCH RESISTANT ALUMINA BASED COATINGS Silecs OY (FI) 2013-02-06 EP disclosed
WO-2011121166-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2011-10-06 WO disclosed