Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549570 | 0.95 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28347564 | 0.95 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL63717 | 0.94 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL220912 | 0.93 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8188277 | 0.92 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1098411 | 0.92 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL218857 | 0.91 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| Alcohol SCHEMBL28778173 | 0.91 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28098839 | 0.91 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5191072 | 0.90 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463493-A | The polymer substrate on the surface with the biomolecule adherency for possessing reduction and the thermoplastic article of this substrate | SIO2医药产品公司 | 2018-08-28 | — | — | CN | disclosed |