Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25498770 | 0.89 | HRH3 (0.35) | ACHE | |
| SCHEMBL25499913 | 0.89 | ACHE (0.34) | ACHEKDM4EHTT | |
| SCHEMBL25498193 | 0.88 | S1PR1 (0.36) | ACHE | |
| SCHEMBL25498247 | 0.88 | MLNR (0.35) | ACHE | |
| SCHEMBL25498172 | 0.88 | KDM4E (0.32) | KDM4EHTT | |
| SCHEMBL25498219 | 0.87 | S1PR1 (0.36) | ACHE | |
| SCHEMBL25498273 | 0.86 | ACHE (0.33) | ACHELMNAMAPTHTT | |
| SCHEMBL25499867 | 0.86 | S1PR1 (0.36) | ACHEALOX15 | |
| SCHEMBL25498237 | 0.85 | HRH3 (0.34) | ACHEHTR6 | |
| SCHEMBL25499152 | 0.85 | HRH2 (0.33) | ACHEHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4177255-A1 | OXADIAZOLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2023-05-10 | — | — | EP | disclosed |