Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 6/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 3/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541603 | 0.86 | INPPL1 (0.50) | IDO1ESR1ESR2MEN1KMT2A | |
| SCHEMBL27595065 | 0.85 | IDO1 (0.45) | IDO1ESR1ESR2MEN1KMT2A | |
| Benzene SCHEMBL28642827 | 0.83 | IDO1 (0.46) | IDO1ESR1ESR2MEN1KMT2A | |
| SCHEMBL9274496 | 0.78 | TSHR (0.44) | IDO1ESR1ESR2KMT2AUSP2 | |
| SCHEMBL234536 | 0.78 | SRC (0.48) | MEN1KMT2A | |
| Toluene SCHEMBL28657685 | 0.77 | ESR1 (0.41) | IDO1ESR1ESR2MEN1KMT2A | |
| SCHEMBL1581774 | 0.76 | IDO1 (0.65) | IDO1ESR1ESR2MEN1KMT2A | |
| SCHEMBL2547019 | 0.76 | IDO1 (0.57) | IDO1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8384662 | 0.74 | INPPL1 (0.57) | ESR1ESR2MEN1KMT2AGAA | |
| SCHEMBL1685758 | 0.74 | GAA (0.53) | KMT2AGAAJAK2USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10155973-B2 | Methods for detecting organisms and enzymatic reactions using raman spectroscopy and aromatic compounds comprising phosphate | SWORD DIAGNOSTICS, INC. (US) | 2018-12-18 | — | — | US | disclosed |
| US-20150218615-A1 | METHODS FOR DETECTING ORGANISMS AND ENZYMATIC REACTIONS USING RAMAN SPECTROSCOPY AND AROMATIC COMPOUNDS COMPRISING PHOSPHATE | SWORD DIAGNOSTICS, INC. (US) | 2015-08-06 | — | — | US | disclosed |
| EP-2553117-A1 | METHODS FOR DETECTING RAMAN SCATTERING USING AROMATIC COMPOUNDS COMPRISING PHOSPHATE AND AT LEAST ONE NON-LASER LIGHT SOURCE | Sword Diagnostics, Inc. (US) | 2013-02-06 | — | — | EP | disclosed |
| WO-2011123386-A1 | METHODS FOR DETECTING RAMAN SCATTERING USING AROMATIC COMPOUNDS COMPRISING PHOSPHATE AND AT LEAST ONE NON-LASER LIGHT SOURCE | KUNDU SAMAR KUMAR (US) | 2011-10-06 | — | — | WO | disclosed |
| US-20100041016-A1 | METHODS FOR DETECTING ORGANISMS AND ENZYMATIC REACTIONS USING RAMAN SPECTROSCOPY AND AROMATIC COMPOUNDS COMPRISING PHOSPHATE | SWORD DIAGNOSTICS, INC. | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041016-A1 | METHODS FOR DETECTING ORGANISMS AND ENZYMATIC REACTIONS USING RAMAN SPECTROSCOPY AND AROMATIC COMPOUNDS COMPRISING PHOSPHATE | PNP, ARSA, PGLS | IDO1 1969/4885ESR1 3147/4885ESR2 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.