SCHEMBL25501050

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23902950	0.89	KDM4E (0.55)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL24513417	0.78	KDM4E (0.71)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL24513420	0.78	KDM4E (0.71)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL23902934	0.78	NPC1 (0.51)	NPC1RAB9AGABRA1GABRG2GABRB3
	SCHEMBL26226937	0.78	KDM4E (0.53)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL26226942	0.78	SMN1; SMN2 (0.53)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL26227186	0.78	KDM4E (0.56)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL23903031	0.77	RAB9A (0.53)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL23903192	0.77	KDM4E (0.60)	KDM4EHPGDHSD17B10NPC1LMNA
	SCHEMBL24513170	0.77	KDM4E (0.57)	KDM4EHPGDHSD17B10NPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.