Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 11/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GLB1 | P16278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23475112 | 1.00 | GBA1 (0.46) | GBA1GAASMN1; SMN2GBA2MGAM | |
| SCHEMBL14071748 | 0.86 | SMN1; SMN2 (0.38) | GBA1GAASMN1; SMN2GLB1 | |
| SCHEMBL12560830 | 0.86 | SMN1; SMN2 (0.38) | GBA1GAASMN1; SMN2GLB1 | |
| SCHEMBL24791134 | 0.86 | SMN1; SMN2 (0.42) | GBA1GAASMN1; SMN2GBA2 | |
| SCHEMBL24789551 | 0.86 | SMN1; SMN2 (0.42) | GBA1GAASMN1; SMN2GBA2 | |
| SCHEMBL21138054 | 0.86 | SMN1; SMN2 (0.38) | GBA1GAASMN1; SMN2GLB1 | |
| SCHEMBL24789558 | 0.86 | SMN1; SMN2 (0.42) | GBA1GAASMN1; SMN2GBA2 | |
| SCHEMBL12560836 | 0.82 | CA1 (0.48) | GBA1GAASMN1; SMN2GLB1 | |
| SCHEMBL13906058 | 0.82 | CA1 (0.48) | GBA1GAASMN1; SMN2GLB1 | |
| SCHEMBL7703115 | 0.82 | GBA1 (0.63) | GBA1GAAGBA2MGAMGLB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088291-A1 | AROMATIC AMINE COMPOUND AND APPLICATION THEREOF | 武汉众诚康健生物医药科技有限公司 | 2023-05-25 | — | — | WO | disclosed |