Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.63 |
| ▸ | GLB1 | P16278 | 1/20 | 0.55 |
| ▸ | GBA2 | Q9HCG7 | 8/20 | 0.49 |
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
| ▸ | UGCG | Q16739 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | AGL | P35573 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703107 | 1.00 | GBA1 (0.63) | GBA1GLB1GBA2GUSBUGCG | |
| SCHEMBL4473375 | 0.85 | GLB1 (0.53) | GBA1GLB1GBA2GUSBUGCG | |
| SCHEMBL13607587 | 0.85 | GLB1 (0.53) | GBA1GLB1GBA2GUSBUGCG | |
| SCHEMBL4473378 | 0.85 | GLB1 (0.53) | GBA1GLB1GBA2GUSBUGCG | |
| SCHEMBL4473371 | 0.85 | GLB1 (0.53) | GBA1GLB1GBA2GUSBUGCG | |
| SCHEMBL7706522 | 0.82 | GBA1 (0.46) | GBA1GLB1GBA2UGCG | |
| SCHEMBL7706516 | 0.82 | GBA1 (0.46) | GBA1GLB1GBA2UGCG | |
| SCHEMBL23475112 | 0.82 | GBA1 (0.46) | GBA1GLB1GBA2GAAMGAM | |
| SCHEMBL25501186 | 0.82 | GBA1 (0.46) | GBA1GLB1GBA2GAAMGAM | |
| SCHEMBL17702822 | 0.79 | GUSB (0.51) | GBA1GLB1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880500-B1 | ESTERS OF 3-HYDROXY-PIPERIDINEMETHANOL DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2002-07-31 | — | — | EP | disclosed |
| EP-0880500-A1 | ESTERS OF 3-HYDROXY-PIPERIDINEMETHANOL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997030031-A1 | ESTERS OF 3-HYDROXY-PIPERIDINEMETHANOL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-08-21 | — | — | WO | disclosed |