SCHEMBL2550140

SCHEMBL2550140

Cc1nc(S(C)(=O)=O)ccc1OC1CCC(OC2CCN(C(=S)OC(C)C)CC2)CC1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 19/20 0.84
CYP2C9 P11712 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2554962 0.91 GPR119 (1.00) GPR119CYP2C9
SCHEMBL12282977 0.91 GPR119 (1.00) GPR119CYP2C9
SCHEMBL14634344 0.87 GPR119 (0.71) GPR119CYP2C9
SCHEMBL12282715 0.85 GPR119 (0.84) GPR119CYP2C9
SCHEMBL14634290 0.85 GPR119 (0.84) GPR119CYP2C9
SCHEMBL14634294 0.85 GPR119 (0.84) GPR119CYP2C9
SCHEMBL12282718 0.83 GPR119 (0.81) GPR119
SCHEMBL14634425 0.83 GPR119 (0.81) GPR119
SCHEMBL14634226 0.83 GPR119 (0.81) GPR119
SCHEMBL2552149 0.83 GPR119 (0.81) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2556056-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO Arena Pharmaceuticals, Inc. (US) 2013-02-13 EP disclosed
WO-2011127051-A1 MODULATORS OF THE GPR119 RECEPTOR AND THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2011-10-13 WO disclosed