SCHEMBL25501513

SCHEMBL25501513

Clc1cc(Cl)c2c(c1)C1(c3c(-c4ccccc4)cccc3-2)C2CC3CC(C2)CC1C3

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.37
HSD11B1 P28845 3/20 0.34
CYP2A6 P11509 1/20 0.33
FABP4 P15090 2/20 0.32
FABP5 Q01469 2/20 0.32
SLC6A3 Q01959 1/20 0.32
ACLY P53396 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25501502 0.86 PDK2 (0.36) PDK2HSD11B1CYP2A6SLC6A3ACLY
SCHEMBL25501694 0.84 PDK2 (0.32) PDK2
SCHEMBL25501373 0.82 PDK2 (0.48) PDK2HSD11B1
SCHEMBL25501500 0.81 PDK2 (0.38) PDK2HSD11B1NPSR1
SCHEMBL25501499 0.81 PDK2 (0.39) PDK2HSD11B1NPSR1
SCHEMBL25501480 0.81 PDK2 (0.34) PDK2HSD11B1ACLYNPSR1
SCHEMBL30593282 0.79 PDK2 (0.40) PDK2HSD11B1CYP2A6SLC6A3MEN1
SCHEMBL25582581 0.79 PDK2 (0.40) PDK2HSD11B1CYP2A6SLC6A3MEN1
SCHEMBL25452143 0.74 PDK2 (0.42) PDK2HSD11B1
SCHEMBL25501565 0.73 PDK2 (0.41) PDK2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11655206-B2 Nitrogen-containing compound, electronic element, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-23 US disclosed
US-11655206-B2 Nitrogen-containing compound, electronic element, and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11655206-B2 Nitrogen-containing compound, electronic element, and electronic device MNS1, NOS1, NPM1 PDK2 3769/4885HSD11B1 4403/4885CYP2A6 2649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.