Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25074184 | 1.00 | CRBN (0.57) | CRBNDDB1POLB | |
| Hydrochloric Acid SCHEMBL30778439 | 0.83 | CRBN (0.51) | CRBNDDB1POLB | |
| SCHEMBL24832965 | 0.82 | CRBN (0.60) | CRBNDDB1POLB | |
| SCHEMBL25501957 | 0.80 | CRBN (0.65) | CRBNDDB1POLB | |
| SCHEMBL29990479 | 0.79 | CRBN (0.60) | CRBNDDB1POLB | |
| SCHEMBL24670590 | 0.79 | CRBN (0.60) | CRBNDDB1POLB | |
| SCHEMBL25074524 | 0.79 | CRBN (0.60) | CRBNDDB1POLB | |
| SCHEMBL30778437 | 0.79 | CRBN (0.69) | CRBNDDB1POLB | |
| SCHEMBL30066434 | 0.79 | CRBN (0.60) | CRBNDDB1POLB | |
| SCHEMBL25074141 | 0.79 | CRBN (0.60) | CRBNDDB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |