⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16283591 | 0.81 | — | — | |
| SCHEMBL27823310 | 0.77 | — | — | |
| SCHEMBL1560977 | 0.77 | — | — | |
| SCHEMBL273776 | 0.75 | — | — | |
| SCHEMBL599850 | 0.75 | — | — | |
| SCHEMBL29408229 | 0.75 | — | — | |
| SCHEMBL10925625 | 0.75 | — | — | |
| SCHEMBL30683717 | 0.75 | — | — | |
| SCHEMBL23266021 | 0.71 | — | — | |
| SCHEMBL669218 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207300-A1 | COMBINATION THERAPIES INCLUDING MYT1 INHIBITORS | SINAI HEALTH SYSTEM (CA) | 2024-06-27 | — | — | US | disclosed |
| US-20230158022-A1 | METHODS OF USING MYT1 INHIBITORS | REPARE THERAPEUTICS INC. (CA) | 2023-05-25 | — | — | US | disclosed |
| US-20230151014-A1 | COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARING COMPOUNDS AND OF THEIR USE | REPARE THERAPEUTICS INC. (CA) | 2023-05-18 | — | — | US | disclosed |