SCHEMBL4585366

SCHEMBL4585366

CC(C)OC(=O)C(C)C(=O)OC(C)C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
HCAR2 Q8TDS4 1/20 0.40
CA12 O43570 7/20 0.36
CA1 P00915 7/20 0.36
CA2 P00918 7/20 0.36
CA9 Q16790 7/20 0.36
CA7 P43166 4/20 0.36
CA14 Q9ULX7 4/20 0.36
LMNA P02545 3/20 0.36
ADRA1A P35348 1/20 0.34
PDE4D Q08499 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 2/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL622787 0.89 TSHR (0.43) TSHRHCAR2CA12CA1CA2
SCHEMBL6520334 0.81 TSHR (0.42) TSHRHCAR2CA12CA1CA2
SCHEMBL6520341 0.81 TSHR (0.42) TSHRHCAR2CA12CA1CA2
SCHEMBL295903 0.80
SCHEMBL28965299 0.80 TSHR (0.53) TSHRHCAR2CA12CA1CA2
SCHEMBL19543396 0.79 TSHR (0.36) TSHRLMNA
SCHEMBL7100772 0.79 TSHR (0.40) TSHRHCAR2CA12CA1CA2
SCHEMBL11631683 0.79 TSHR (0.40) TSHRHCAR2LMNAALDH1A1
SCHEMBL6180156 0.78
SCHEMBL141671 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
EP-3053935-B1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME CHINA PETROLEUM & CHEM CORP (CN) 2019-05-08 EP claimed
US-9822196-B2 Catalyst composition for olefin polymerization and application of same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-11-21 US claimed
CN-107075223-A Emulsion polymers, emulsion processes and polymer compositions comprising one or more 1, 1-disubstituted alkene compounds 赛鲁斯股份有限公司 2017-08-18 CN claimed
CN-104513330-B A kind of catalyst systems for olefin polymerization and its application 中国石油化工股份有限公司 2017-07-28 CN claimed
CN-104513332-B Catalyst system and its application for olefinic polymerization 中国石油化工股份有限公司 2017-06-06 CN claimed
US-20160244538-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-08-25 US claimed
EP-3053935-A1 CATALYST COMPOSITION FOR OLEFIN POLYMERIZATION AND APPLICATION OF SAME China Petroleum & Chemical Corporation (CN) 2016-08-10 EP claimed
CN-105315390-A Catalyst composition for olefin polymerization and application thereof BEIJING COMBINE TECH CO LTD 2016-02-10 CN claimed
CN-104910001-A Synthetic method of 5-chloro-1-indanone XU WEI 2015-09-16 CN claimed
CN-104513330-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513327-A Olefin polymerization catalyst composition and applications thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-104513332-A Catalyst system used in olefin polymerization and application thereof CHINA PETROLEUM & CHEMICAL 2015-04-15 CN claimed
CN-101337874-B Method for preparing indanone compounds SHANGHAI RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) 2011-12-14 CN claimed
CN-101337874-A Method for preparing indanone compounds SHANGHAI CHEMICAL ACADEMY (CN) 2009-01-07 CN claimed
CN-118909170-A Catalyst system for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-114805647-B Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2024-03-29 CN disclosed
CN-1561346-A Solid catalyst component for olefin polymerization IDEMITSU PETROCHEMICAL CO (JP) 2005-01-05 CN disclosed
US-20040102310-A1 Solid catalyst component for olefin polymerization IDEMITSU KOSAN CO., LTD. (JP) 2004-05-27 US disclosed
EP-1396503-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-03-10 EP disclosed