Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825430 | 0.71 | — | — | |
| SCHEMBL16215642 | 0.70 | CARM1 (0.41) | CARM1PRMT6PRMT8HRH3L3MBTL1 | |
| SCHEMBL1967223 | 0.67 | — | — | |
| SCHEMBL11209430 | 0.64 | HRH3 (0.44) | CARM1PRMT6PRMT8HRH3L3MBTL1 | |
| SCHEMBL23056803 | 0.63 | HRH3 (0.42) | CARM1PRMT6PRMT8HRH3L3MBTL1 | |
| SCHEMBL5148484 | 0.63 | — | — | |
| SCHEMBL12674258 | 0.63 | CARM1 (0.38) | CARM1PRMT6PRMT8HRH3L3MBTL1 | |
| SCHEMBL1967252 | 0.61 | — | — | |
| SCHEMBL23056837 | 0.61 | HRH3 (0.46) | CARM1PRMT6PRMT8HRH3L3MBTL1 | |
| SCHEMBL12665774 | 0.61 | CARM1 (0.37) | CARM1PRMT6PRMT8HRH3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121309-A1 | PHENYL SULFONYL DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-10-06 | — | — | WO | disclosed |