Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953531 | 0.92 | POLB (0.52) | POLBABL1RIN1RNASE1ADRB1 | |
| SCHEMBL21886710 | 0.92 | POLB (0.52) | POLBABL1RIN1RNASE1ADRB1 | |
| SCHEMBL6466613 | 0.92 | POLB (0.52) | POLBABL1RIN1RNASE1ADRB1 | |
| SCHEMBL25504697 | 0.90 | POLB (0.46) | POLBABL1RIN1RNASE1 | |
| SCHEMBL26537753 | 0.90 | POLB (0.45) | POLBABL1RIN1ADRB1DNMT1 | |
| SCHEMBL8583929 | 0.85 | POLB (0.44) | POLBRNASE1 | |
| SCHEMBL25512274 | 0.85 | POLB (0.42) | POLBABL1RIN1RNASE1 | |
| SCHEMBL25521895 | 0.84 | POLB (0.41) | POLBABL1RIN1ADRB1DNMT1 | |
| SCHEMBL9780701 | 0.84 | POLB (0.51) | POLBABL1RIN1ADRB1DNMT1 | |
| SCHEMBL9780708 | 0.84 | POLB (0.51) | POLBABL1RIN1ADRB1DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |