Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25504696 | 0.90 | POLB (0.46) | POLBABL1RIN1RNASE1 | |
| SCHEMBL21886710 | 0.85 | POLB (0.52) | POLBABL1RIN1RNASE1 | |
| SCHEMBL6466613 | 0.85 | POLB (0.52) | POLBABL1RIN1RNASE1 | |
| SCHEMBL5953531 | 0.85 | POLB (0.52) | POLBABL1RIN1RNASE1 | |
| SCHEMBL25765241 | 0.82 | MAPT (0.43) | POLBABL1RIN1MAPTCYP1A2 | |
| SCHEMBL12404712 | 0.82 | POLB (0.66) | POLBABL1RIN1CYP2C9SMN1; SMN2 | |
| SCHEMBL26455112 | 0.81 | ABL1 (0.40) | POLBABL1RIN1RNASE1CYP2C9 | |
| SCHEMBL26455083 | 0.81 | ABL1 (0.42) | POLBABL1RIN1RNASE1MAPT | |
| SCHEMBL13714438 | 0.81 | P2RY6 (0.44) | POLBABL1RIN1MAPTCYP1A2 | |
| SCHEMBL26537753 | 0.80 | POLB (0.45) | POLBABL1RIN1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |