SCHEMBL25504782

SCHEMBL25504782

CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)[C@@H](O[Si](C)(C)C)[C@@H]2O[Si](C(C)C)(C(C)C)O1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.34
▸ SLC28A2 O43868 1/20 0.34
▸ SLC29A1 Q99808 1/20 0.34
▸ SLC28A3 Q9HAS3 1/20 0.34
▸ DUT P33316 1/20 0.34
▸ P2RY2 P41231 4/20 0.33
▸ P2RY6 Q15077 4/20 0.33
▸ TDP1 Q9NUW8 1/20 0.32
▸ P2RY14 Q15391 3/20 0.32
▸ STING1 Q86WV6 1/20 0.32
▸ P2RY4 P51582 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9893207 0.92 SLC28A1 (0.34) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL706579 0.90 TDP1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL26780258 0.90 TDP1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL16243030 0.88 SLC28A1 (0.33) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL25134191 0.87 SLC28A1 (0.33) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12114737 0.87 SLC28A1 (0.33) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL1318144 0.87 SLC28A1 (0.33) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL17972429 0.87 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL12170354 0.87 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
SCHEMBL25400489 0.87 SLC28A1 (0.35) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 — — US disclosed
US-20230159922-A1 MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF IONIS PHARMACEUTICALS, INC. (US) 2023-05-25 — — US disclosed
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