SCHEMBL26780258

SCHEMBL26780258

CC(=O)O[C@@H]1[C@@H]2O[Si](C(C)C)(C(C)C)O[Si](C(C)C)(C(C)C)OC[C@H]2O[C@H]1n1ccc(=O)[nH]c1=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.41
▸ SLC28A1 O00337 1/20 0.34
▸ SLC28A2 O43868 1/20 0.34
▸ SLC29A1 Q99808 1/20 0.34
▸ SLC28A3 Q9HAS3 1/20 0.34
▸ P2RY2 P41231 2/20 0.34
▸ P2RY6 Q15077 2/20 0.34
▸ P2RY14 Q15391 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL706579 1.00 TDP1 (0.41) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL16863925 0.91 TDP1 (0.34) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1318516 0.90 TDP1 (0.41) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25504782 0.90 SLC28A1 (0.34) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL9893207 0.90 SLC28A1 (0.34) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL9964294 0.89 TDP1 (0.36) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL16594078 0.88 TDP1 (0.42) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL1317537 0.86 TDP1 (0.36) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL29707946 0.86 TDP1 (0.35) TDP1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL25608882 0.86 TDP1 (0.35) TDP1SLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 — — US disclosed
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES INC 2023-11-30 — — US disclosed
WO-2023215516-A2 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF HELIX NANOTECHNOLOGIES, INC. (US) 2023-11-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230383287-A1 ACETYLATED RIBONUCLEIC ACIDS AND USES THEREOF NSUN2, NSUN3, ADAR TDP1 464/4885SLC28A1 988/4885SLC28A2 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback