SCHEMBL25508591

SCHEMBL25508591

CC1CC2(CCN(C3CC4(CCN(C5CCC6(CC5)CNC6)CC4)C3)CC2)C1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.31
L3MBTL3 Q96JM7 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24185456 0.97 HRH3 (0.32) HRH3L3MBTL3L3MBTL1
SCHEMBL26052331 0.84 HRH3 (0.36) HRH3
SCHEMBL26752530 0.83 HRH3 (0.33) HRH3
SCHEMBL26748933 0.82 HRH3 (0.34) HRH3L3MBTL3L3MBTL1
SCHEMBL25518551 0.81 HRH3 (0.32) HRH3
SCHEMBL25814798 0.81 CYP1A2 (0.33) HRH3L3MBTL3L3MBTL1
SCHEMBL26053190 0.80 HRH3 (0.37) HRH3
SCHEMBL24185427 0.80 KDM4E (0.38) L3MBTL3L3MBTL1
SCHEMBL22737182 0.80 CYP1A2 (0.33) HRH3L3MBTL3L3MBTL1
SCHEMBL346805 0.78 L3MBTL3 (0.38) HRH3L3MBTL3L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357193-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF XIZANG HAISCO PHARMACEUTICALS CO., LTD. (CN) 2023-11-09 US disclosed
EP-4180427-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF Sichuan Haisco Pharmaceutical Co., Ltd. (CN) 2023-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357193-A1 COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF AR, CYP17A1, KLK3 HRH3 2130/4885L3MBTL3 2966/4885L3MBTL1 2305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.