Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 13/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19662117 | 0.91 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL19642435 | 0.91 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL19662652 | 0.91 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL29548036 | 0.91 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL19642359 | 0.89 | NOTUM (0.53) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL29547609 | 0.89 | NOTUM (0.53) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL29547997 | 0.89 | TTR (0.49) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL19642374 | 0.89 | TTR (0.49) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL29548530 | 0.87 | TTR (0.47) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL19642422 | 0.87 | TTR (0.47) | TTRNOTUMHTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11661420-B2 | Compound containing fused ring, use thereof and pharmaceutical composition containing same | NANJING HEPO PHARMACEUTICAL CO., LTD (CN) | 2023-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11661420-B2 | Compound containing fused ring, use thereof and pharmaceutical composition containing same | HLA-B, HLA-A, SLC10A1 | TTR 596/4885NOTUM 116/4885HTR1A 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.