Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 13/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19642422 | 1.00 | TTR (0.47) | TTRNOTUMCSF1RHTR1AHTR7 | |
| SCHEMBL19642374 | 0.90 | TTR (0.49) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL29547997 | 0.90 | TTR (0.49) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL25510580 | 0.87 | TTR (0.52) | TTRNOTUMHTR1AHTR7HTR6 | |
| SCHEMBL21130153 | 0.86 | SUV39H2 (0.45) | TTR | |
| SCHEMBL19642435 | 0.86 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL19662117 | 0.86 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL29548036 | 0.86 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL19662652 | 0.86 | NOTUM (0.56) | TTRNOTUM | |
| SCHEMBL29547609 | 0.84 | NOTUM (0.53) | TTRNOTUMHTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311860-B | Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases | 豪夫迈·罗氏有限公司 | 2022-04-08 | — | — | CN | disclosed |