Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 13/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15246438 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL25500452 | 0.81 | CHRNB2 (0.36) | EPHX2 | |
| SCHEMBL18247666 | 0.77 | HPGD (0.46) | SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL21077867 | 0.74 | KMT2A (0.54) | EPHX2 | |
| SCHEMBL26141153 | 0.71 | EPHX2 (0.38) | SMN1; SMN2EPHX1EPHX2 | |
| SCHEMBL24568867 | 0.70 | — | — | |
| SCHEMBL18339480 | 0.67 | GRM2 (0.32) | — | |
| SCHEMBL38655537 | 0.67 | GRM2 (0.32) | — | |
| SCHEMBL17875088 | 0.67 | EPHX1 (0.55) | EPHX1EPHX2 | |
| SCHEMBL3317490 | 0.67 | EPHX2 (0.42) | SMN1; SMN2EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083365-A1 | PAD4 INHIBITORS AND USE THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2023-05-19 | — | — | WO | disclosed |