Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 4/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114276 | 0.92 | TMIGD3 (0.40) | TMIGD3ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL25512274 | 0.86 | POLB (0.42) | TMIGD3POLBABL1RIN1 | |
| SCHEMBL2114275 | 0.84 | POLB (0.34) | TMIGD3ADORA2APOLBHSP90AA1HSP90AB1 | |
| SCHEMBL22984016 | 0.82 | TYMP (0.46) | TMIGD3ADORA3ADORA1POLB | |
| SCHEMBL261967 | 0.82 | TYMP (0.46) | TMIGD3ADORA3ADORA1POLB | |
| SCHEMBL21828786 | 0.82 | TYMP (0.46) | TMIGD3ADORA3ADORA1POLB | |
| SCHEMBL25512063 | 0.81 | POLB (0.33) | TMIGD3ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL7599198 | 0.80 | TMIGD3 (0.36) | TMIGD3ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL7651302 | 0.80 | TMIGD3 (0.36) | TMIGD3ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL332975 | 0.78 | POLB (0.51) | TMIGD3ADORA3POLBHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |