Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14670972 | 0.89 | TSHR (0.30) | — | |
| SCHEMBL24827890 | 0.84 | HRH3 (0.43) | OPRL1HRH3 | |
| SCHEMBL26050466 | 0.83 | OPRL1 (0.41) | OPRL1OPRM1OPRK1HRH3OPRD1 | |
| SCHEMBL25507794 | 0.83 | OPRL1 (0.36) | OPRL1OPRM1OPRK1HRH3OPRD1 | |
| SCHEMBL24185519 | 0.82 | OPRL1 (0.36) | OPRL1OPRM1OPRK1HRH3OPRD1 | |
| SCHEMBL24185878 | 0.81 | KDM4E (0.34) | HRH3 | |
| SCHEMBL25471070 | 0.79 | HRH3 (0.32) | HRH3 | |
| SCHEMBL22737160 | 0.79 | HRH3 (0.32) | HRH3 | |
| SCHEMBL25508556 | 0.79 | HRH3 (0.32) | HRH3 | |
| SCHEMBL25855358 | 0.79 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180427-A1 | COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |