Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25513993 | 0.88 | CNR2 (0.46) | CNR2CNR1KDM4E | |
| SCHEMBL25514207 | 0.87 | CNR2 (0.42) | CNR2CNR1KDM4E | |
| SCHEMBL12907719 | 0.83 | CNR2 (0.70) | CNR2CNR1 | |
| SCHEMBL25509478 | 0.81 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL13532091 | 0.80 | CNR1 (0.48) | CNR2CNR1 | |
| SCHEMBL29388169 | 0.77 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL922969 | 0.77 | CNR2 (0.77) | CNR2CNR1 | |
| SCHEMBL24208982 | 0.77 | CNR1 (0.56) | CNR2CNR1 | |
| SCHEMBL22244945 | 0.76 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL12918536 | 0.75 | CNR1 (0.54) | CNR2CNR1KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023089612-A1 | PERIPHERAL CB1 RECEPTOR ANTAGONISTS FOR TREATMENT OF LOWER URINARY TRACT SYMPTOMS (LUTS) | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2023-05-25 | — | — | WO | disclosed |