Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25514196 | 0.90 | BRD4 (0.54) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL25514185 | 0.83 | BRD4 (0.54) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL25514178 | 0.83 | BRD4 (0.54) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL25514004 | 0.81 | BRD4 (0.52) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL25514182 | 0.80 | BRD4 (0.51) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL23174927 | 0.76 | BRD4 (0.49) | BRD4HDAC1HDAC6TSHRLMNA | |
| SCHEMBL21410459 | 0.76 | BRD4 (0.76) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL1053390 | 0.74 | HPGD (0.50) | BRD4SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL21410171 | 0.74 | BRD4 (0.50) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 | |
| SCHEMBL21423952 | 0.73 | L3MBTL1 (0.57) | BRD4HDAC1HDAC6SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159554-A1 | COMPOUND WITH ANTICANCER ACTIVITY | KYOWA KIRIN CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159554-A1 | COMPOUND WITH ANTICANCER ACTIVITY | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, RCC2 | BRD4 2025/4885HDAC1 6/4885HDAC6 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.