SCHEMBL25705679

SCHEMBL25705679

c1ccc(N2CN(c3cccc4c3oc3ccccc34)c3nccnc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.41
HSD17B10 Q99714 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 3/20 0.41
HPGD P15428 2/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HCRTR1 O43613 1/20 0.41
TP53 P04637 1/20 0.41
MAPK1 P28482 1/20 0.41
DRD4 P21917 1/20 0.40
LMNA P02545 3/20 0.38
LIMK1 P53667 1/20 0.35
CYP2C19 P33261 1/20 0.34
CA9 Q16790 1/20 0.34
HRH4 Q9H3N8 3/20 0.34
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PIK3CD O00329 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25575381 0.91 TSHR (0.41) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL24913473 0.91 TSHR (0.41) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL26262393 0.86 DRD4 (0.39) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL24850981 0.86 PIK3CA (0.38) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL25801450 0.83 MAPT (0.38) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL22311187 0.83 DRD4 (0.37) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL25514834 0.82 TSHR (0.38) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL12100521 0.81 DRD4 (0.39) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL25835075 0.80 ALDH1A1 (0.40) TSHRHSD17B10MEN1KMT2AMAPT
SCHEMBL25515303 0.80 PIK3CA (0.31) TSHRHSD17B10MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 US disclosed
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-02 US disclosed
US-11778897-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-10-03 US disclosed
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 US disclosed
US-20230200211-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-22 US disclosed
US-11678565-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-13 US disclosed
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same UNIVERSAL DISPLAY CORPORATION (US) 2023-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647667-B2 Organic electroluminescent compounds and organic light emitting devices using the same OCIAD1, OCIAD2, ODC1 TSHR 3962/4885HSD17B10 1057/4885MEN1 2465/4885
US-11778897-B2 Organic electroluminescent materials and devices LIFR, LBR, ZFR TSHR 168/4885HSD17B10 4353/4885MEN1 3677/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 TSHR 398/4885HSD17B10 2728/4885MEN1 3516/4885
US-11737349-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC TSHR 4305/4885HSD17B10 1074/4885MEN1 2207/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 TSHR 939/4885HSD17B10 3153/4885MEN1 2774/4885
US-11678565-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OPRD1 TSHR 4662/4885HSD17B10 1509/4885MEN1 3172/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP TSHR 1042/4885HSD17B10 1521/4885MEN1 4145/4885
US-20230200211-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OPRM1, OCIAD1 TSHR 1460/4885HSD17B10 3087/4885MEN1 1473/4885
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 TSHR 2901/4885HSD17B10 2347/4885MEN1 3473/4885
US-20230192738-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRM1, OPRD1, OXER1 TSHR 850/4885HSD17B10 3032/4885MEN1 1982/4885
US-20230354692-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, LBR, ZFR TSHR 168/4885HSD17B10 4353/4885MEN1 3677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.