Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.62 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22789989 | 0.87 | NR1H4 (0.59) | NR1H4HSD17B13 | |
| SCHEMBL28375306 | 0.86 | NR1H4 (0.64) | NR1H4HSD17B13 | |
| SCHEMBL20833613 | 0.86 | NR1H4 (0.63) | NR1H4HSD17B13 | |
| SCHEMBL26923025 | 0.85 | NR1H4 (0.62) | NR1H4HSD17B13 | |
| SCHEMBL22078599 | 0.84 | NR1H4 (0.61) | NR1H4HSD17B13 | |
| SCHEMBL21912532 | 0.84 | NR1H4 (0.61) | NR1H4HSD17B13 | |
| SCHEMBL20632491 | 0.83 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL1096074 | 0.83 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL22654652 | 0.83 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL22654654 | 0.83 | NR1H4 (0.60) | NR1H4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667629-B2 | Isoxazole derivative, preparation method therefor, and use thereof | SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-06-06 | — | — | US | disclosed |
| CN-110128432-A | Tricyclic nitrogen containing compounds and its application in drug | 广东东阳光药业有限公司 | 2019-08-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667629-B2 | Isoxazole derivative, preparation method therefor, and use thereof | CYP4A11, CYP4F11, SLC10A1 | NR1H4 6/4885HSD17B13 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.