Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.64 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25515573 | 0.86 | NR1H4 (0.62) | NR1H4HSD17B13 | |
| SCHEMBL20419535 | 0.86 | NR1H4 (0.63) | NR1H4HSD17B13 | |
| SCHEMBL29904887 | 0.86 | NR1H4 (0.63) | NR1H4HSD17B13 | |
| SCHEMBL22789989 | 0.83 | NR1H4 (0.59) | NR1H4HSD17B13 | |
| SCHEMBL20833613 | 0.82 | NR1H4 (0.63) | NR1H4HSD17B13 | |
| SCHEMBL26923025 | 0.82 | NR1H4 (0.62) | NR1H4HSD17B13 | |
| SCHEMBL22078599 | 0.81 | NR1H4 (0.61) | NR1H4HSD17B13 | |
| SCHEMBL21912532 | 0.81 | NR1H4 (0.61) | NR1H4HSD17B13 | |
| SCHEMBL22654654 | 0.80 | NR1H4 (0.60) | NR1H4HSD17B13 | |
| SCHEMBL20632491 | 0.80 | NR1H4 (0.60) | NR1H4HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818704-A | Spiro-bridged ring compounds, pharmaceutical compositions thereof and uses thereof | 广州市恒诺康医药科技有限公司 | 2020-02-21 | — | — | CN | disclosed |