Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GLP1R | P43220 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516119 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL25516113 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL12743488 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL19261664 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL13034893 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL25516086 | 0.94 | MEN1 (0.46) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL13684293 | 0.93 | EPHX2 (0.43) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL23518687 | 0.91 | MEN1 (0.46) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL21011153 | 0.90 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AEPHX2TSHR | |
| SCHEMBL21172275 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AEPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078813-A1 | HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |