Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10142032 | 0.98 | KDM4E (0.60) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL5668591 | 0.92 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXTSHR | |
| SCHEMBL8342578 | 0.88 | HPGD (0.53) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL18947953 | 0.88 | HPGD (0.53) | KDM4EMAPK1HIF1APAOXEPHX2 | |
| SCHEMBL23946005 | 0.86 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL19983194 | 0.86 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL24508669 | 0.86 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL22856378 | 0.85 | EPHX2 (0.51) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL23560302 | 0.85 | KDM4E (0.59) | KDM4EMAPK1HIF1APAOXKMT2A | |
| SCHEMBL22525950 | 0.85 | KDM4E (0.59) | KDM4EMAPK1HIF1APAOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086979-A1 | STAGGERED TRIPLE LIPID-MODIFIED NUCLEIC ACID COMPOUNDS | DTX PHARMA, INC. (US) | 2023-05-19 | — | — | WO | disclosed |