Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.39 |
| ▸ | YTHDF2 | Q9Y5A9 | 1/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25615714 | 0.81 | CHRM4 (0.40) | CHRM4 | |
| SCHEMBL23264081 | 0.77 | CSF1R (0.37) | CHRM4CSF1RYTHDC1YTHDF2PDPK1 | |
| SCHEMBL25466895 | 0.77 | CSF1R (0.37) | CHRM4CSF1RYTHDC1YTHDF2PDPK1 | |
| SCHEMBL14567010 | 0.76 | YTHDC1 (0.48) | CSF1RYTHDC1YTHDF2PDPK1EGFR | |
| SCHEMBL23942854 | 0.75 | CHRM4 (0.37) | CHRM4 | |
| SCHEMBL25778227 | 0.73 | CHRM4 (0.34) | CHRM4CSF1RYTHDC1 | |
| SCHEMBL22143319 | 0.73 | MEN1 (0.35) | CHRM4PDPK1CYP1A2JAK3CYP2D6 | |
| SCHEMBL1661906 | 0.72 | PDE10A (0.42) | CHRM4 | |
| SCHEMBL18819275 | 0.70 | GSK3B (0.47) | — | |
| SCHEMBL14983681 | 0.70 | YTHDC1 (0.44) | CSF1RYTHDC1YTHDF2PDPK1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083285-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |