Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 6/20 | 0.52 |
| ▸ | CDK9 | P50750 | 6/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.52 |
| ▸ | CDK2 | P24941 | 5/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25517483 | 0.84 | CCNT1 (0.47) | CCNT1CDK9CCNA2CDK2HTR2A | |
| SCHEMBL25156831 | 0.81 | JAK2 (0.52) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL25157854 | 0.77 | JAK2 (0.54) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL25158196 | 0.76 | DYRK1A (0.54) | CCNT1CDK9CCNA2CDK2JAK2 | |
| SCHEMBL25158199 | 0.75 | MAPT (0.45) | CCNT1CDK9CCNA2CDK2JAK2 | |
| SCHEMBL15436437 | 0.75 | CDK9 (0.53) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL3985729 | 0.72 | AHR (0.59) | CYP1A1CYP1B1KDM4EALDH1A1MAPT | |
| SCHEMBL26174610 | 0.71 | DYRK1A (0.52) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL414693 | 0.69 | CDK9 (0.54) | CCNT1CDK9CCNA2CDK2CDK5 | |
| SCHEMBL12347465 | 0.69 | CDK9 (0.73) | CCNT1CDK9CCNA2CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | VICKERS VENTURE FUND VI PTE. LTD. (SG) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167133-A1 | 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF | DYRK1A, DYRK1B, DYRK2 | CCNT1 1162/4885CDK9 94/4885CCNA2 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.