Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384867 | 0.91 | PPARA (0.43) | PPARAPPARGPPARDCYP2A6TAAR1 | |
| SCHEMBL2700588 | 0.83 | SIGMAR1 (0.52) | CYP2A6TAAR1 | |
| SCHEMBL12664322 | 0.82 | TSHR (0.42) | PPARACYP2A6TAAR1 | |
| SCHEMBL2557004 | 0.82 | SLC6A2 (0.53) | PPARAPPARGFFAR1AGXTIDO1 | |
| SCHEMBL1840449 | 0.82 | TAAR1 (0.53) | PPARATAAR1 | |
| SCHEMBL24049214 | 0.82 | PPARA (0.41) | PPARAPPARGPPARDTAAR1 | |
| SCHEMBL1109064 | 0.82 | TSHR (0.42) | PPARACYP2A6TAAR1 | |
| SCHEMBL13457372 | 0.82 | TAAR1 (0.53) | PPARATAAR1 | |
| SCHEMBL13430495 | 0.81 | AGXT (0.40) | PPARAPPARGPPARDFFAR1AGXT | |
| SCHEMBL9263881 | 0.80 | SLC6A4 (0.58) | PPARAPPARGPPARDIDO1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2555623-A1 | FLAVIN DERIVATIVES | BioRelix, Inc. (US) | 2013-02-13 | — | — | EP | disclosed |
| WO-2011126567-A1 | FLAVIN DERIVATIVES | BIORELIX, INC. (US) | 2011-10-13 | — | — | WO | disclosed |