Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL302421 | 1.00 | TSHR (0.43) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL27515430 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL27676475 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL27382255 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL28189090 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL27392847 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL27521126 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL28046076 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| Bromide SCHEMBL7136237 | 0.96 | TSHR (0.40) | TSHRLMNATHRBDNM1ALDH1A1 | |
| SCHEMBL51248 | 0.96 | TSHR (0.46) | TSHRLMNATHRBDNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122011891-A | Hydrogen-microorganism synergistic corrosion protection coating and preparation method and application thereof | 中国科学院金属研究所 | 2026-05-12 | — | — | CN | claimed |
| CN-115806654-B | Difunctional epoxy resin latent curing agent and preparation method and application thereof | 浙江理工大学 | 2025-06-17 | — | — | CN | claimed |
| CN-120132731-A | PH-sensitive molded coal spontaneous combustion inhibition microcapsule and preparation method and application thereof | 辽宁工程技术大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120081743-A | Synthesis method of fluxapyroxad intermediate trifluoro-nitrobiphenyl | 辽宁众辉生物科技有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120051184-A | Multi-dimensional perovskite solar cell with wide processing window and preparation method thereof | 中国长江三峡集团有限公司 | 2025-05-27 | — | — | CN | claimed |
| CN-119978264-A | Tentacle type double-cation modified tannin-based organic flocculant and preparation method and application thereof | 山东大学 | 2025-05-13 | — | — | CN | claimed |
| CN-119431939-B | Preparation process of Hou Zuran-resistant sheath material and optical cable thereof | 天津立孚光电科技股份有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119819363-A | Catalyst system for hydrochlorination of acetylene and application thereof | 石河子大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119823090-A | Method for preparing glycolide by catalyzing methyl glycolate through metal-based ionic liquid | 郑州中科新兴产业技术研究院 | 2025-04-15 | — | — | CN | claimed |
| CN-119786575-A | Sodium iron sulfate composite material and preparation method and application thereof | 深圳先进技术研究院 | 2025-04-08 | — | — | CN | claimed |
| CN-111704784-A | Process method for regenerating foam plastic from waste polyester bottle and printed circuit board | 邓素荣 | 2020-09-25 | — | — | CN | claimed |
| CN-111435705-A | Repairing agent and repairing method thereof and method for preparing photoelectric film | 杭州纤纳光电科技有限公司 | 2020-07-21 | — | — | CN | claimed |
| WO-2020132940-A1 | MACROMONOMERIC STABILIZER, PREPARATION METHOD THEREOF, AND METHOD FOR PREPARING POLYMERIC POLYOL | 万华化学集团股份有限公司 | 2020-07-02 | — | — | WO | claimed |
| CN-107803222-B | Ruthenium complex catalyst for acetylene hydrochlorination | 浙江工业大学 | 2020-06-09 | — | — | CN | claimed |
| CN-110627943-A | Preparation method of cationic alkyl super-concentrated emulsion polymer for coating | 湖北工业大学 | 2019-12-31 | — | — | CN | claimed |
| CN-110627963-A | Preparation method of quaternary ammonium salt and quaternary phosphonium salt cation core-shell emulsion polymer | 湖北工业大学 | 2019-12-31 | — | — | CN | claimed |
| CN-110591008-A | Preparation method of cationic alkyl core-shell emulsion polymer | 湖北工业大学 | 2019-12-20 | — | — | CN | claimed |
| CN-105254490-B | Process for extracting succinic acid by microcapsules | 南京工业大学 | 2017-06-06 | — | — | CN | claimed |
| US-9522915-B2 | Method for preparing an important intermediate of linagliptin | 2Y-CHEM, LTD. (CN) | 2016-12-20 | — | — | US | claimed |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | 2Y-CHEM, LTD. (CN) | 2015-10-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | DPP4, DPP9, DPP3 | TSHR 3222/4885LMNA 1729/4885THRB 3071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.