Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2551829 | 0.96 | TSHR (0.43) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL302421 | 0.96 | TSHR (0.43) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL27392847 | 0.93 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL27521126 | 0.93 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL27676475 | 0.93 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL27382255 | 0.93 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL28189090 | 0.93 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL7136237 | 0.93 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| Bromide SCHEMBL27515430 | 0.93 | TSHR (0.40) | TSHRLMNATHRBSLC22A1SLC22A2 | |
| SCHEMBL51248 | 0.93 | TSHR (0.46) | TSHRLMNATHRBSLC22A1SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105684096-B | Conductive paste, connection structure, and method for producing connection structure | 积水化学工业株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-105209541-B | Methacrylic resin composition and its formed body | 株式会社可乐丽 | 2017-12-12 | — | — | CN | disclosed |
| CN-105209501-B | Film | 株式会社可乐丽 | 2017-09-26 | — | — | CN | disclosed |
| CN-106471055-A | Methacrylic resin composition and its manufacture method, formed body, thin film and polarization plates | 株式会社可乐丽 | 2017-03-01 | — | — | CN | disclosed |
| CN-105684096-A | Conductive paste, connection structure, and method for producing connection structure | 积水化学工业株式会社 | 2016-06-15 | — | — | CN | disclosed |
| CN-105209541-A | Methacrylic resin composition and molded body thereof | KURARAY CO | 2015-12-30 | — | — | CN | disclosed |
| CN-105209501-A | Film | KURARAY CO | 2015-12-30 | — | — | CN | disclosed |