Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440918 | 0.85 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL2620677 | 0.79 | CHRM1 (0.49) | CHRM1SLC6A2SLC6A4HTR4 | |
| SCHEMBL22113083 | 0.79 | CHRM1 (0.49) | CHRM1SLC6A2SLC6A4HTR4 | |
| SCHEMBL23519812 | 0.79 | CHRM1 (0.49) | CHRM1SLC6A2SLC6A4HTR4 | |
| SCHEMBL2612625 | 0.77 | ALDH1A1 (0.36) | CHRM1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL14388282 | 0.75 | KCNH2 (0.38) | CHRM1SLC6A2SLC6A4SLC6A3HTR4 | |
| SCHEMBL2612617 | 0.75 | CHRM1 (0.35) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL24467163 | 0.75 | CHRM1 (0.35) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL22251721 | 0.75 | CHRM1 (0.35) | CHRM1SLC6A2SLC6A4 | |
| SCHEMBL24301474 | 0.75 | CHRM1 (0.35) | CHRM1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081662-A1 | BICYCLIC DERIVATIVES AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |