Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23635234 | 0.86 | SMYD2 (0.31) | SMYD2 | |
| SCHEMBL25518968 | 0.84 | CYP3A4 (0.36) | CYP3A4MAPK1BACE1 | |
| SCHEMBL10322922 | 0.79 | BACE1 (0.32) | SMYD2CYP3A4MAPK1BACE1 | |
| SCHEMBL12509355 | 0.79 | BACE1 (0.32) | SMYD2CYP3A4MAPK1BACE1 | |
| SCHEMBL15935851 | 0.79 | BACE1 (0.32) | SMYD2CYP3A4MAPK1BACE1 | |
| SCHEMBL24673063 | 0.73 | SMYD2 (0.32) | SMYD2CYP3A4MAPK1HTTSMN1; SMN2 | |
| SCHEMBL12573485 | 0.71 | CYP3A4 (0.32) | CYP3A4MAPK1 | |
| SCHEMBL12269674 | 0.70 | SMYD2 (0.32) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL1139972 | 0.70 | BACE1 (0.36) | SMYD2CYP3A4MAPK1HTTSMN1; SMN2 | |
| SCHEMBL12269801 | 0.69 | SMYD2 (0.31) | SMYD2CYP3A4HTTSMN1; SMN2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649475-B2 | Dioxetane compounds and their use for the detection of microorganisms | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649475-B2 | Dioxetane compounds and their use for the detection of microorganisms | DAXX, LITAF, EDF1 | SMYD2 3812/4885CYP3A4 140/4885MAPK1 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.