Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25519026 | 0.87 | ESR1 (0.40) | ESR1 | |
| SCHEMBL19204565 | 0.85 | ESR1 (0.56) | ESR1CYP1A2 | |
| SCHEMBL31014158 | 0.85 | ESR1 (0.42) | ESR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL19204574 | 0.85 | ESR1 (0.48) | ESR1 | |
| SCHEMBL31014156 | 0.83 | ESR1 (0.41) | ESR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL31014141 | 0.83 | CYP1A1 (0.45) | ESR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL31014165 | 0.83 | ESR1 (0.43) | ESR1CYP1A1CYP1A2CYP1B1 | |
| Iodide SCHEMBL31014149 | 0.82 | ESR1 (0.40) | ESR1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL31014154 | 0.82 | NPC1 (0.40) | ESR1 | |
| SCHEMBL25519032 | 0.79 | ESR1 (0.33) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649475-B2 | Dioxetane compounds and their use for the detection of microorganisms | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649475-B2 | Dioxetane compounds and their use for the detection of microorganisms | DAXX, LITAF, EDF1 | ESR1 1223/4885CYP1A1 12/4885CYP1A2 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.