Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068374 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23150505 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23150503 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL23150504 | 0.86 | EPHX1 (0.44) | EPHX1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13712559 | 0.83 | EPHX1 (0.52) | EPHX1ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL27638306 | 0.83 | HSD11B1 (0.48) | EPHX1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL159496 | 0.82 | USP30 (0.48) | GPR119USP30KDM4EPKMJAK2 | |
| SCHEMBL4721171 | 0.82 | EPHX1 (0.47) | EPHX1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16692970 | 0.81 | EPHX1 (0.40) | EPHX1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL17936450 | 0.80 | EPHX1 (0.62) | EPHX1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012031024-A1 | BICYCLIC OXAZOLE AND THIAZOLE COMPOUNDS AND THEIR USE AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS | VANDERBILT UNIVERSITY (US) | 2012-03-08 | — | — | WO | disclosed |