Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.69 |
| ▸ | CTSB | P07858 | 2/20 | 0.69 |
| ▸ | CAPN1 | P07384 | 6/20 | 0.60 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28951163 | 1.00 | CTSL (0.69) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL28951162 | 1.00 | CTSL (0.69) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL30205476 | 0.89 | CTSL (0.74) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL15985617 | 0.89 | CTSL (0.74) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL28951332 | 0.89 | CTSL (0.58) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL25519904 | 0.89 | CTSL (0.58) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL28951335 | 0.89 | CTSL (0.58) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL28951322 | 0.89 | CTSL (0.59) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL28951316 | 0.89 | CTSL (0.59) | CTSLCTSBCAPN1CTSSCTSK | |
| SCHEMBL25529097 | 0.89 | CTSL (0.59) | CTSLCTSBCAPN1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | COCRYSTAL PHARMA, INC. | 2023-05-25 | — | — | US | disclosed |
| EP-4132944-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | Cocrystal Pharma, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| CN-115698035-A | Inhibitors of norovirus and coronavirus replication | 共晶制药公司 | 2023-02-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159453-A1 | INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION | VIM, ACE, ACE2 | CTSL 1031/4885CTSB 1058/4885CAPN1 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.